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    • SYT3抗原（重組蛋白）

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW17272
      • 應(yīng)用 : 僅供科研使用
      • 保存條件 : 低溫保存
      • 貨期 : 現(xiàn)貨
      • 商品庫(kù)存：40
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    中文名稱： SYT3抗原（重組蛋白）

    英文名稱： SYT3 Antigen (Recombinant Protein)

    別      名： SytIII

    儲(chǔ)      存： 冷凍（-20℃）

    相關(guān)類別： 抗原

    概述

    Fusion protein corresponding to a region derived from 76-200 amino acids of human SYT3

    技術(shù)規(guī)格

    Full name:

    synaptotagmin III

    Synonyms:

    SytIII

    Swissprot:

    Q9BQG1

    Gene Accession:

    BC031067

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.