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    • GAR1抗原（重組蛋白）

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW16639
      • 應(yīng)用 : 僅供科研使用
      • 保存條件 : 低溫保存
      • 貨期 : 現(xiàn)貨
      • 商品庫(kù)存：60
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    中文名稱： GAR1抗原（重組蛋白）

    英文名稱： GAR1 Antigen (Recombinant Protein)

    別     名： NOLA1

    儲(chǔ)     存： 冷凍（-20℃）

    相關(guān)類別： 抗原

    概     述

    Full length fusion protein

    技術(shù)規(guī)格

    Full name:

    GAR1 homolog, ribonucleoprotein

    Synonyms:

    NOLA1

    Swissprot:

    Q9NY12

    Gene Accession:

    BC003413

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.