購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
RAPGEF1 |
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Immunogen: |
Fusion protein of human RAPGEF1 |
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Full name: |
Rap guanine nucleotide exchange factor (GEF) 1 (RAPGEF1), transcript variant 2 |
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Synonyms: |
C3G; GRF2 |
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SwissProt: |
Q13905 |
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IHC positive control: |
human breast tissue and carcinoma of human thyroid tissue; carcinoma of human prostate tissue and adenocarcinoma of human colon tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
121 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
500-2000 |
